For each family in version 8.1 of RFam listed in the drop down below, an alignment was performed using PMFastR. Each sequences was separated from the alignment and the structural annotation removed. The first sequence (as ordered by RFam) retained the structural annotation. Each sequence (other than the first) was fed into PMFastR individually. The results of the alignment procedure as well as the original RFam alignment are displayed below for manual examination. The alignment metrics for each of the alignments are displayed in the manuscript.
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The raw files are also available via links below.
Note: The structure was assigned to the first sequence in the Rfam data, then the first alignment was with its own sequence without structure, this was used as the seed for all subsiquent alignments, therefore the first two lines of our output are the same sequence